sequences and api are ok
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@ -1,7 +1,6 @@
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# app/models.py
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from sqlalchemy import Column, Integer, String, Text, ForeignKey
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from sqlalchemy.orm import relationship
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from .database import Base
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from app.database import Base
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class Sequence(Base):
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__tablename__ = "sequences"
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@ -1,5 +1,3 @@
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#%%
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# entrypoint.py
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from Bio import SeqIO
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from sqlalchemy.orm import Session
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from app.database import engine, SessionLocal, Base
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@ -9,7 +7,6 @@ import json
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# Tworzenie tabeli w bazie danych
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Base.metadata.create_all(bind=engine)
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#%%
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def get_db():
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db = SessionLocal()
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try:
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@ -25,25 +22,38 @@ def load_genbank_to_db(file_path: str):
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# Zapisz sekwencję do bazy danych
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sequence_data = Sequence(
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name=record.name,
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description=record.description,
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description=record.description if 'description' in record.annotations else 'No description',
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sequence=str(record.seq)
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)
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db.add(sequence_data)
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db.commit()
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db.refresh(sequence_data) # Odśwież sekwencję, aby uzyskać jej ID
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# Zapisz cechy (features) do bazy danych
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for feature in record.features:
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feature_data = Feature(
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type=feature.type,
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location=str(feature.location),
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sequence=str(record.seq[feature.location.start:feature.location.end]),
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qualifiers=json.dumps(feature.qualifiers),
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sequence_id=sequence_data.id
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)
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db.add(feature_data)
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if feature.type in ["promoter", "RBS","CDS", "protein_bind", "misc_feature", "rep_origin", "terminator"]:
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qualifiers = {}
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if feature.type == "CDS":
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qualifiers['gene_name'] = feature.qualifiers.get('gene', ['Unknown gene'])[0]
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qualifiers['product'] = feature.qualifiers.get('product', ['Unknown product'])[0]
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elif feature.type == "protein_bind":
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qualifiers['binding_site'] = feature.qualifiers.get('bound_moiety', ['Unknown binding site'])[0]
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elif feature.type == "misc_feature":
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qualifiers['note'] = feature.qualifiers.get('note', ['No additional information'])[0]
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elif feature.type == "rep_origin":
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qualifiers['note'] = "This is a replication origin."
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feature_data = Feature(
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type=feature.type,
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location=str(feature.location),
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sequence=str(record.seq[feature.location.start:feature.location.end]),
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qualifiers=json.dumps(qualifiers),
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sequence_id=sequence_data.id # Ustawienie poprawnego ID
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)
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db.add(feature_data)
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db.commit()
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print(f"Loaded {file_path} to database.")
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if __name__ == "__main__":
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load_genbank_to_db("data/pET-28+(a).gb")
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load_genbank_to_db("data/plasmid.gb")
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